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hmtoggle_plus1Churg-Strauss syndrome:  ARA (4 of 6) -
1.asthma
a defining feature of CSS
precedes other manifestations
in contrast to common asthma, it develops at a later age
2.eosinophilia  (>10% of WBC)
3.mononeuritis multiplex
4.non-fixed pulmonary infiltrate
5.paranasal sinus abnormalities
6.extravascular eosinophils on biopsy

 

 

hmtoggle_plus1Kawasaki Disease

Fever for 5 or more days plus four of the five following criteria:

1.conjunctivitis
2.injected or red tongue, pharynx, or lips
3.erythema of the palms or soles, edema of the hands and feet, or periungual desquamation
4.polymorphous exanthem
5.cervical lymphadenopathy

 

(easier name to remember – mucocutaneous lymph node disease)

 

 

hmtoggle_plus1Neurofibromatosus 1
·need 2 of 7;   mnemonic = CAN FOOL

 

1.café au lait macules (6 or more)
2.axillary or groin freckling
3.neurofibromas (2 or more)
4.first-degree relative with 2 criteria
5.optic glioma
6.o – characteristic bony deformities (??)
7.Lisch nodules

 

 

Adult Still’s Disease Criteria:

Presence of all of the following:

Fever >39°C
arthralgia or arthritis
RF < 1:80
ANA < 1:100

In addition to any two of the following:

WBC >15,000 cells/mm3
Still’s rash
pleuritis or pericarditis
hepatomegaly or splenomegaly or generalized LAN

 

 

Jones Criteria (updated 1992) for diagnosis of Acute Rheumatic Fever:

Requires evidence of preceding group A strep infection and the presence of two major or one major and two minor manifestations:

Major manifestations:

carditis
polyarthritis
chorea
subcutaneous nodules
erythema marginatum

 

 

 

 

 

Minor manifestations:

arthralgia
fever
elevated ESR or C-reactive protein
prolonged P-R interval

Supporting evidence of antecedent group A streptococcal infection:

positive throat culture
positive rapid strep antigen test
elevated or rising strep antibody titer (e.g. ASO etc…)