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extended 5 L's ddx:
| • | rare disease; etiology unknown |
| • | a misnomer: not granulomatous (called so on basis of color) |
| • | red/brown papules, plaques or nodules (usually solitary) that have patulous follicular ostia |
| • | notoriously resistant to treatment |
| • | histology: (distinctive) diffuse inflammatory cell infiltrate of neutrophils and eosinophils; Grenz zone; LCV |
clinical ddx:
| • | LE, PMLE, fixed drug, leukemic infiltrate, and the whole spectrum of benign and malignant lymphoid proliferation |
| • | granulomatous process: sarcoid, GA, and foreign body reactions to infectious processes such as tinea faciale, leprosy, and TB |
vs. EED:
| • | GF and EED appear to be closely related and perhaps different manifestations of the same disease |
| • | EED (vasculitis and neutrophils: resembles ganuloma faciale but is without eosinophils, and found on dorsal aspect of hands and elbows) |
| • | Sweet’s - (lots of neutrophils but no LCV) |
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