By Disease Name > Hydroa Vacciniforme

Hydroa Vacciniforme

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childhood;  very rare
recurring crops of papulovesicles resolve with pock-like scarring
might represent a “scarring” variant of PMLE
boys; usually only during summer months;  resolves in adolescence (like actinic prurigo)
hydroa estivale = mild form with little scarring
treatment: beta-carotene, anti-malarials
ddx:  often misdiagnosed as HSV, because they present with vesicles after a day at the beach;   EPP (scars), check plasma protoporphyrins

 

summary:

actinic prurigo (eczematous) (girls); probably an “excoriated” variant of PMLE
hydroa vacciniforme (papulovesicular) (boys); might represent a “scarring” variant of PMLE

 

histology:

distinctive:  intraepidermal blister;  focal epidermal keratinocyte necrosis and spongiosis with perivascular neutrophils and lymphocytic infiltrate