Differential Diagnosis > Distribution > Lower Legs > Leg Ulcers

Leg Ulcers

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(most common to less common)

venous stasis
arterial disease
neurotropic
sickle cell ulcer lower legs, moderate pain, often "punched out"
hypertensive
hydroxyurea can cause severe painful leg ulcers (discontinuation heals)

 

see also Wound Healing

 

 

Venous stasis ulcers:

location medial ankle or lower calf
symptoms painless or mild
characteristics red base of granulation tissue; surrounding hyperpigmentation; depth: shallow; warm feet
Venous disease: dermatitis and pitting edema
see also Venous Stasis spectrum

 

Arterial ulcers (due to large vessels):

location usually toes or foot;  lateral aspect of ankle
symptoms severe pain
characteristics black or gray base;  no granulation tissue; depth: deep;  cold feet
cause arteriosclerosis obliterans, thromboangiitis obliterans
Arterial disease: shiny, dry, atrophic surface with heel and toe fat pad diminution  

 

Neurotropic ulcers:

location over metatarsal arch, heel, toes
symptoms no pain
characteristics deep and surrounded by callus
cause diabetes and other neuropathies

 

Hypertensive ulcers:

lateral and posterior calf;  severe pain
black eschar surrounded by purpura
etiology unknown