(most common to less common)
• | hydroxyurea can cause severe painful leg ulcers (discontinuation heals) |
see also Wound Healing
Venous stasis ulcers:
• | location – medial ankle or lower calf |
• | symptoms – painless or mild |
• | characteristics – red base of granulation tissue; surrounding hyperpigmentation; depth: shallow; warm feet |
Arterial ulcers (due to large vessels):
• | location – usually toes or foot; lateral aspect of ankle |
• | characteristics – black or gray base; no granulation tissue; depth: deep; cold feet |
• | cause – arteriosclerosis obliterans, thromboangiitis obliterans |
Neurotropic ulcers:
• | location – over metatarsal arch, heel, toes |
• | characteristics – deep and surrounded by callus |
• | cause – diabetes and other neuropathies |
Hypertensive ulcers:
• | lateral and posterior calf; severe pain |
• | black eschar surrounded by purpura |
|