By Disease Name > Lymphangioma circumscriptum

Lymphangioma circumscriptum

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uncommon but distinctive hamartomatous malformations
the malformations consist of a collection of subcutaneous lymphatic cisterns with a thick muscle coat that communicate with the clinically apparent superficial vesicles*, via dialed channels lined with lymphatic endothelium
* “frog spawn”  (filled with clear or blood tinged fluid)
may appear in the setting of post-mastectomy lymphedema as a result of lymphatic damage following surgery and radiation AKA secondary lymphangioma (lymphangiectasis)
treatment:  surgical removal of the subcutaneous cisterns (residual skin vesicles separated from their underlying cysts regress)