• | comprises more than one entity; acquired and familial forms (autosomal dominant) |
• | = a group of chronic disorders |
• | reddish-orange; islands of sparing |
• | nails – thickened, brittle (rarely if ever pit) |
• | histology: alternating vertical and horizontal parakeratosis |
• | prognosis – classic adult type 80% clear by 3 years |
• | treatment: high dose vitamin A; (Shupak says – Accutane 2mg/kg/day X 6 months); Soriatane; etanercept |
• | psoriasis-like; ddx – psoriasis, phrynoderma, SCLE |
Griffiths classification type I-V:
• | three juvenile onset forms with poor prognosis for involution |
type I adult onset, classical
• | ~ orderly cephalocaudal progression |
• | spontaneous resolution in 80% of patients in 1 to 3 years |
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