Diagnostic Tests > Autoantibodies > Sensitivity and Specificity

Sensitivity and Specificity

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Antibody:

Disease:

Sensitive or Specific:

 

 

 

nDNA

SLE

Specific

 

 

 

histone

drug LE

Sensitive

 

 

 

U1RNP

MCTD

Sensitive (100% by definition)

 

 

 

Anti-Sm

SLE

Specific

 

 

 

Scl-70

PSS

Specific

 

 

 

ANA

SLE, CREST, PSS, MCTD

Sensitive

 

 

 

Centromere

CREST

Sensitive AND Specific

 

 

 

c-ANCA

Wegeners Granulomatosis

Sensitive AND Specific