By Disease Name > Sjogrens syndrome

Sjogrens syndrome

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>90% women
skin - LCV (patients with cutaneous vasculitis have a high prevelance of peripheral or CNS vasculitis)
labs - rheumatoid factor positive (usually), Ro (80%)
definitive diagnosis:  labial salivary gland biopsy from lower lip
ddx:  sarcoid, amyloid, lymphoma, HIV

 

2 out of 3:

1.xeropthalmia
2.xerostomia
3.an associated autoimmune, rheumatic, or lymphoproliferative disorder patients are predisposed to lymphoreticular malignancies (e.g. non-Hodgkins)