|
general rules:
| • | adequate length of time for a trial of “avoidance” ~ 2 months |
| • | the allergen is usually of low molecular weight (a hapten) and lipid soluble (i.e. must penetrate the stratum corneum) |
allergen:
|
significance:
|
|
|
alstromeria
|
#1 flower causing contact dermatitis in florists in US
|
(Peruvian Lily)
|
|
|
|
Balsam of Peru
|
fragrances
|
|
|
dinitrochlorobenzene
|
|
|
|
ethylene diamine
|
|
|
|
monobenzylether of hydroquinone
|
chemical vitiligo
|
|
|
parabens
|
creams and cosmetics (common preservatives)
|
|
|
paraphenylene diamine
|
in hair dyes; melanotoxic (chemical vitiligo)
|
|
|
potassium dichromate
|
cement, chrome-tanned leathers
|
|
|
Quaternium 15
|
cosmetics and skin care products
|
|
|
toluene formaldehyde resin
(AKA tosylamide formaldehyde resin)
|
nail varnish
|
Favorite board questions
| most common of allergic contact dermatitis to shoes = | a rubber component allergy (usually mercaptobenzothiazole and less frequently to thiurams) |
formaldehyde releasing preservatives: quaternuium-15,
imidazolidinyl urea
dimethylgyoxime – used to identify compounds that contain nickel
|