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| • | persistent, relapsing, multisystemic |
classic triad (oral, genital, ocular):
| • | consider Behcet's if such lesions occur more than 3 times a year along with two other symptoms: recurrent genital ulceration, retinal vasculitis, erythema-nodosum like lesions, or acneiform skin lesions (but non-follicular) |
| • | other causes of recurrent oral ulcerations, such as HSV and IBD, must be excluded |
| • | scrotum is predominant site in men; vulva in women; can scar |
| • | once one eye is affected, both will be inevitably |
| • | posterior uveitis, progresses to blindness if not treated |
pathergy reaction = at the site of a needle puncture, a pustule surrounded by erythema may occur
arthritis: (50%) oligoarthritic, nondestructive
GI: (50%) lesions are small ulcerations (resembling orogenital aphthae); abdominal pain and GI bleed are chief symptoms
treatment: colchicine, thalidomide, dapsone
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