• | T-Cell Receptor gene rearrangement: |
• | CTPL (10-19% are clonal) |
• | CTCL (up to 90% are clonal) |
• | CTPL (compared with CBPL) = a more heterogenous group, and in most cases the cause is known (e.g. drug, contact, bite, light (i.e. actinic reticuloid) |
Histology:
Immunohistochemistry:
a heterogenous group:
• | the infiltrate is much less dense than CTPL and is arranged primarily perivascularly |
• | as a rule, atypical lymphocytes and lymphoid follicles are not present |
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