| • | photosensitizing (200mg/day = often photosensitive, may get away with 100mg/day) |
| • | doxycycline (hyclate or monohydrate) - monohydrate less GI tract upset |
| • | 100mg BID is effective against each of the "big three" |
| • | Lyme disease (if < 8 years old, then amoxicillin) |
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for what it is worth:
| • | I have prescribed doxycycline almost daily for over 8 years to patients (5 of the years practicing in sunny Florida) and I have seen doxycycline photosensitivity exactly one time (the patient had a blistering sunburn, especially on her dorsal hands, after hiking in the Grand Canyon) |
| • | I prescribe minocycline daily (again for over 8 years) - I have had one case of blue pigmentation (on the legs of a man with venous stasis - it cleared a few months after discontinuation of the drug); I have had three cases of minocycline-induced serum-sickness (urticaria and fairly severe migratory arthritis - two of the patients ended up in the ER; everyone resolved with steroids) |
rosacea in patient with chronic kidney disease:
| • | Doxycycline (over other tetracyclines) is excreted primarily via the GI tract, and its half-life is not substantially increased by renal failure |
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