By Disease Name > Hand, Foot, and Mouth Disease

Hand, Foot, and Mouth Disease

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pathogen = coxsackie A16
mild symptoms of low grade fever, sore-throat
enanthem: 90%;  apthae-like erosions, small and asymptomatic
cutaneous lesions:  2/3 of patients…
within 24 hours of enanthem
red macules that rapidly become pale, white, oval to cigar-shaped vesicles with a red areola
hands and feet, especially palms and soles
heal in 7 days without crusting or scarring
no treatment needed

 

culture virus from stool;  acute and convalescent serum titers
histology:  reticular degeneration (multilocular blisters vs. herpes virus)