| • | adverse effects: hyperpigmentation, vertigo |
| • | autoimmune adverse effects (very rare): drug-LE, autoimmune hepatitis |
for what it is worth:
| • | I have prescribed doxycycline almost daily for over 8 years to patients (5 of the years practicing in sunny Florida) and I have seen doxycycline photosensitivity exactly one time (the patient had a blistering sunburn, especially on her dorsal hands, after hiking in the Grand Canyon) |
| • | I prescribe minocycline daily (again for over 8 years) - I have had one case of blue pigmentation (on the legs of a man with venous stasis - it cleared a few months after discontinuation of the drug); I have had three cases of minocycline-induced serum-sickness (urticaria and fairly severe migratory arthritis - two of the patients ended up in the ER; everyone resolved with steroids) |
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