• | AKA exanthematous drug eruption |
• | most consistent with a type IV delayed hypersensitivity reaction (?) |
• | usually 1-2 days after starting drug (almost always within 1-2 weeks) |
• | blood eosinophilia = a non-specific finding that is often absent |
• | ddx: viral exanthem, scarlet fever, staph scarlatiniform eruption, toxic shock syndrome, acute GVHD, eruption of lymphocyte recovery, juvenile RA |
• | pearl - always elicit contrast dye or blood product/transfusion history as well |
drug vs. infectious:
• | drug – suddenly without prodrome (“drug red”) |
• | infectious – often with prodrome |
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