Differential Diagnosis > Other > Specific Patients > Cancer Patient > More Dermatoses and Malignancies

More Dermatoses and Malignancies

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hmtoggle_plus1Skin lesions where histology = infiltrating cancer cells:

Purple plums        

 

       

 

       

 

       

1 – vascular tumor

2 – lymphoreticular malignancy

3 – soft tissue malignancy

4 – amelanotic melanoma

5 - metastasis

 

Carcinoma Cuirasse

local breast mets

 

Carcinoma Erysipelatoides

local breast mets

 

Exfoliative Erythroderma

CTCL

 

 

hmtoggle_plus1Conditions that resolve when underlying CA is treated (only to return with a relapse of the CA) are:
1.dermatomyositis
2.hypertrichosis lanuginosa
3.erythema gyratum repens

 

 

hmtoggle_plus1GI tract malignancies:

Sign of Leser Trelat        

 

       

GI tract (esp. stomach)

Hypertrichosis lanuginosa (malignant down)        

GI tract (esp. colon)

 

Acanthosis Nigricans

below  the diaphragm

 

Muir-Torre syndrome

colon cancer (most commonly)

 

Gardner’s syndrome

colon cancer

 

 

hmtoggle_plus1Lymphoreticular malignancies:

Sweet’s syndrome        

 

hematopoietic (esp. AML)

Paraneoplastic Pemphigus

lymphoproliferative malignancy (esp.non-Hodgkins and CLL)

 

Ichthyosis (acquired)        

Hodgkin’s

 

Ataxia telangiectasia        

lymphoreticular malignancy

 

 

hmtoggle_plus1Lymphoma:
•specific cutaneous lesions are much less frequent in Hodgkin’s disease then in non-Hodgkins lymphoma
•non-specific lesions are characteristic of Hodgkin’s  (e.g. generalized pruritis, prurigo nodularis, acquired ichthyoses (strongly associated ))