• | brand name: Elimite (5% dermal cream) |
• | MOA – acts on nerve cell membranes of parasites, therefore paralyzing exoskeleton muscles that allow lice to breath |
• | active against, lice, ticks, mites, and fleas |
• | it is important that all insecticides are put on dry hair because lice can close down their respiratory airways for one-half hour when immersed in water |
• | treatment of choice for scabies by most dermatologists; about 90% cure after single treatment |
• | excellent safety record; approved for infants aged 2 months or older |
• | unlike lindane, it is rapidly metabolized and does not accumulate in adipose or CNS tissues |
• | adverse effects limited to local burning, irritation |
• | mnemonic: Elimite “permets” the treatment of infants and “elimites” (eliminates) the risk of CNS toxicity |
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