Therapy > Medication > Permethrin

Permethrin

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brand name: Elimite (5% dermal cream)
MOA acts on nerve cell membranes of parasites, therefore paralyzing exoskeleton muscles that allow lice to breath
active against, lice, ticks, mites, and fleas
it is important that all insecticides are put on dry hair because lice can close down their respiratory airways for one-half hour when immersed in water
treatment of choice for scabies by most dermatologists; about 90% cure after single treatment
excellent safety record; approved for infants aged 2 months or older
unlike lindane, it is rapidly metabolized and does not accumulate in adipose or CNS tissues
adverse effects limited to local burning, irritation
mnemonic:  Elimite “permets” the treatment of infants and “elimites” (eliminates) the risk of CNS toxicity