clinical:
• | develops in infants with severe underlying diseases |
• | pathogenesis = increased ratio of saturated to unsaturated fat (therefore higher solid phase temperature; makes sense: lard vs. vegetable oil) |
histology:
• | distinctive changes: adipose cells containing needle-shaped clefts in radial array (crystals) |
• | unlike subcutaneous fat necrosis of the newborn, there is very little inflammation |
classic ddx - subcutaneous fat necrosis of the newborn
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