• | major task is ingestion and elimination of noxious material |
• | 25% of granules in the neutrophil |
• | contain hydrolytic enzymes and peroxidase |
• | major constituent is alkaline phosphatase |
many neutrophilic disease are caused by immune complexes
• | linear IgA bullous dermatitis/ chronic bullous dermatitis of childhood (IgA DIF) |
• | Subcorneal Pustular Dermatosis (IgA subset) |
• | EED (IgA paraproteinemia) |
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• | DH (invariably responds) |
• | EED (invariably responds) |
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